Lab-on-a-chip in Biomedical Applications
Lab-on-a-chip i biomedicinska tillämpningar

EEMN26, 7.5 credits, A (Second Cycle)

Valid for: 2025/26
Faculty: Faculty of Engineering LTH
Decided by: PLED BME
Date of Decision: 2025-04-11
Effective: 2025-05-05

General Information

Depth of study relative to the degree requirements: Second cycle, in-depth level of the course cannot be classified
Elective for: B4, BME4-bf, E4, F4, F4-mt, N4-nbm
Language of instruction: The course will be given in English on demand

Aim

The course gives a detailed technical view of miniaturized bioanalysis and highlights some lab-on-a-chip technologies currently used in clinical medicine and biomedical research. Fundamental principles for bioanalysis integrated in microfluidic systems, where sample handling and detection principles are key areas of interest, are emphasized. These will be penetrated through lectures and lab exercises.

Learning outcomes

Knowledge and understanding
For a passing grade the student must

• be able to identify and present fundamental lab-on-a-chip principles
• be able to identify and present scaling laws within microfluidics and bioanalysis

Competences and skills
For a passing grade the student must

• be able to analyse and describe the function of microfluidics based bioanalysis systemns
• be able to compare and evaluate miniaturized technologies that currently are used within bioanalysis
• be able to analyze and justify the choice of materials for the construction of a lab-on-a-chip system

Judgement and approach
For a passing grade the student must

• be able to evaluate the benefits and drawbacks of miniaturising a given bioanalytical quest

Contents

The course is based on a lecture series that will convey both basic lab-on-a-chip technology and describe how this is applied in modern bioanalysis. Guest lecturers from renowned bioanalysis companies in the region will further point out the importance and value of miniaturized and automated bioanalysis within the healthcare sector and medical research. The course will also encompass laboratory exercises that outline a set of clinically relevant analytical techniques that are based on microfluidics and lab-on-a-chip technology. These exercises aim at giving hands-on experience in the basic construction of microfluidics-based analysis systems and thereby provide a wholistic view of the lab-on-a-chip technology

Examination details

Grading scale: TH - (U, 3, 4, 5) - (Fail, Three, Four, Five)
Assessment: To pass the course approved lab exercise reports and written exam is required

The examiner, in consultation with Disability Support Services, may deviate from the regular form of examination in order to provide a permanently disabled student with a form of examination equivalent to that of a student without a disability.

Modules
Code: 0118. Name: Examination.
Credits: 6.0. Grading scale: TH - (U, 3, 4, 5). Assessment: Approved written exam
Code: 0218. Name: Lab Exercises.
Credits: 1.5. Grading scale: UG - (U, G). Assessment: Approved laboratory work

Admission

Assumed prior knowledge: 3 years of studying at Faculty of Engineering.
The number of participants is limited to: No

Reading list

• Study materials will be delivered during the course.

Contact

Course coordinator: Maria Antfolk, maria.antfolk@bme.lth.se
Course homepage: https://bme.lth.se/course-pages/lab-on-a-chip-i-biomedicinska-tillaempningar/lab-on-a-chip-in-biomedical-applications/